General Information

  • ID:  hor002437
  • Uniprot ID:  NA
  • Protein name:  Leucomyosuppressin
  • Gene name:  NA
  • Organism:  Zophobas atratus
  • Family:  Myosuppressin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EDVDHVFLRF
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T10 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Inhibit spontaneous contraction of muscles
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002437_AF2.pdbhor002437_ESM.pdb

Physical Information

Mass: 143713 Formula: C59H85N15O17
Absent amino acids: ACGIKMNPQSTWY Common amino acids: DFV
pI: 4.37 Basic residues: 2
Polar residues: 0 Hydrophobic residues: 5
Hydrophobicity: -4 Boman Index: -2487
Half-Life / Aliphatic Index: 1 hour Aliphatic Index: 97
Instability Index: 3249 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21067424
  • Title:  Identification of Myotropic Neuropeptides From the Brain and Corpus Cardiacum-Corpus Allatum Complex of the Beetle, Zophobas Atratus